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:: Volume 13, Issue 6 (Feb,Mar 2012) ::
J Shahrekord Univ Med Sci 2012, 13(6): 92-100 Back to browse issues page
Effect of Portulaca oleracea L vice versa silver sulfadiazine on burn wound healing in Balb/c mice
Leila Rafiee-Vardanjani , Najme Sahinfard , Mohamad Rahimi-Madiseh , Roya Ansari-Samani , Marzieh Rahimi , Neda Parvin * , Fatemeh Taji-Eshkaftaki
, E-mail:np285@yahoo.com
Abstract:   (10850 Views)
Background and aim: The effect of herbal medicine with antitoxidant activity on burn wound healing has been proven in various studies. Portulaca oleracea L (Purslane) is a rich source of antioxidants and fatty acids. This study was carried out to compare the effect of purslane and silver on the second-degree burn wound healing in Balb/c mice. Methods: In this preclinical study, burn wounds were made with a hot plate on the back of 85 Balb/c mice. Four groups of mice were treated topically for 21 days by vaseline, silver salfadiazin, 1% and 10% purslane. Wound size on days 0, 7, 14 and 21 were measured. Data were analyzed using Kruskal- Wallis and test. Results: Results showed that the recovery was observed in silver group, 10% purslane, 1% purslane and vaseline, respectively. There was no significant difference in burn wound healing between silver and 10% purslane groups on days 14 and 21 (P>0.05), but significant difference between vaseline and 10% purslane groups on days 14 and 21 (P<0.05). Conclusion: Regarding to the finding of this study, extracts of 10% purslane expedites the wound healing process in mice. Therefor, it might be beneficial in patients with burn wound.
Keywords: Burn wound, Healing, purslane, Silver sulfadiazine
Full-Text [PDF 151 kb]   (3717 Downloads)    
Type of Study: Research |
Received: 2012/02/1 | Accepted: 2017/09/2 | Published: 2017/09/2
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Rafiee-Vardanjani L, Sahinfard N, Rahimi-Madiseh M, Ansari-Samani R, Rahimi M, Parvin N et al . Effect of Portulaca oleracea L vice versa silver sulfadiazine on burn wound healing in Balb/c mice. J Shahrekord Univ Med Sci. 2012; 13 (6) :92-100
URL: http://journal.skums.ac.ir/article-1-986-en.html


Volume 13, Issue 6 (Feb,Mar 2012) Back to browse issues page
مجله دانشگاه علوم پزشکی شهرکرد Journal of Shahrekord University of Medical Sciences
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