:: Volume 4, Issue 3 (autumn 2002) ::
J Shahrekord Univ Med Sci 2002, 4(3): 45-51 Back to browse issues page
The effect of Atropine and Promethazine on the labor process and Apgar score of infants
Masoume Delaram * , Ali Nasimi , Fereshte Aein , Nasrin Forouzande , Azar Danesh
Abstract:   (31662 Views)
Since in most labor departments a mixture of Atropine and Promethazine is used to decrease the labor period, but its effect is still controversial, this randomized clinical trial was performed to assess the effects of this drug mixture on the progress of labor and apgar of infants. 200 pregnant women were randomly assigned to two groups (Case and control). The case group received 0.5 mg Atropine and 25 mg Promethazine. The control group received 2 ml of sterile water. These drugs were injected once at the beginning of the active phase of labor. Labor progress and first Apgar score were recorded. The mean labor progression of the case and control groups in nuliparous women was 253.29 and 231.41 minutes respectively, which didn’t indicate a significant statistical difference. These times in multiparous women were 232.67 and 199.04 minutes. The mean of the second stage of labor was 42.58 and 35.32 minutes in nuliparous women and 11.53 and 11.22 minutes in multiparous women that didn’t indicate a significant difference. The mean of the first Apgar score was not significant between two groups in nuliparous and multiparous women. These findings indicated that Atropine and Promethazine had no positive impact on the progression of the labor and was considered to be a waste of time and medicine.
Keywords: Keywords: Atropine, Promethazine, Labor, Apgar
Full-Text [PDF 1135 kb]   (1686 Downloads)    
Type of Study: Research |
Received: 2011/06/23

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Volume 4, Issue 3 (autumn 2002) Back to browse issues page