[Home ] [Archive]   [ فارسی ]  
:: Main About Current Issue Archive Search Submit Contact ::
:: Volume 19, Number 3 (8-2017) ::
J Shahrekord Univ Med Sci 2017, 19(3): 42-51 Back to browse issues page
Comparative study of oral probiotic and dimethicone on infantile colic
Fatemeh Famoori *, Tahereh Riahi, Mohammad Ali Zamani, Elham Hashemi, Karam Ali Kasiri
Pediatrics Dept., Shahrekord University of Medical Science, Shahrekord, I.R. Iran; Child Growth and Development Research Center, Isfahan University of Medical Sciences, Isfahan, I.R. Iran , fat.famoori@gmail.com
Abstract:   (193 Views)
Background and aims: Infantile colic is one of the most common problems within the first 3 months of life, which affects as many as 3% to 28% of newborn children. It causes appreciable distress for parents and pediatricians even though its pathogenesis remains unclear. The goal was to test the hypothesis that oral administration of probiotic (Lactobacillus reuteri) in a prospective randomized study was improved symptoms of infantile colic.
Methods: This is a case control clinical trial study. Seventy breastfed colicky infants were assigned randomly to receive either the probiotic L. reuteri (108 live bacteria per day) or dimethicone (20 mg/day) three times/day for 28 days.
Results: Seventy infants contain 34 and 36 in the probiotic L. reuteri and dimethicone groups, respectively. Average ages of L. reuteri and dimethicone groups were 41/35 and 43/5 days, respectively. Daily median crying times in the probiotic L. reuteri and dimethicone groups were reduced from initial value about 206 minutes/day on the seventh day to 65 and 141 minutes/day on the 28th day, respectively. Finally, 88% and 9% patients were improved in the probiotic L. reuteri and dimethicone groups, respectively. Furthermore, no adverse effects were reported.
Conclusion: The probiotic L. reuteri has improved colicky symptoms in breastfed infants within 2 weeks of treatment, which suggests that probiotics may have an important role in improving not only criteria of infantile colic but also severity of gas passing of them.
Keywords: Gastrointestinal microbiome, Probiotics, Dimethicone, Infant, Colic.
Full-Text [PDF 829 kb]   (50 Downloads)    
Type of Study: Research | Subject: Pediatrics
Received: 2016/03/21 | Accepted: 2016/09/3 | Published: 2017/08/2
Send email to the article author

Add your comments about this article
Your username or email:

Write the security code in the box >

XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Famoori F, Riahi T, Zamani M A, Hashemi E, Kasiri K A. Comparative study of oral probiotic and dimethicone on infantile colic. J Shahrekord Univ Med Sci. 2017; 19 (3) :42-51
URL: http://journal.skums.ac.ir/article-1-2847-en.html
Volume 19, Number 3 (8-2017) Back to browse issues page
مجله دانشگاه علوم پزشکی شهرکرد Journal of Shahrekord University of Medical Sciences
Persian site map - English site map - Created in 0.05 seconds with 792 queries by yektaweb 3443