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:: Volume 11, Issue 1 (spring 2009) ::
J Shahrekord Univ Med Sci 2009, 11(1): 28-34 Back to browse issues page
Comparative study on the effect of combine low dose contraceptive pills administered by the oral and vaginal routes on bleeding pattern in dysfunctional uterine bleeding
Fariba Abbasi * , Ferdos Mehrabeyan
Gynecologist, Isfahan Univ. of Med. Sci. Iran , noor_m81@yahoo.com
Abstract:   (14439 Views)
Background and aim: It has been shown that contraceptive pills, which are commonly used orally, have some side effects, such as vomiting, nausea, high blood pressure. Vaginally usage of the contraceptive pills reduces these side effects. This study aimed to evaluate and compare the effect of orally and vaginally usage of low dose contraceptive pills on bleeding pattern in dysfunctional uterine bleeding. Methods: In this clinical trial study, 100 women who had been referred to the Shahid-Beheshti and Al-Zahra hospitals of Isfahan as having dysfunctional uterine bleeding were divided into two equal groups. Groups 1 were given contraceptive pills orally and group 2 vaginally. Using pictorial bleeding assessment, the amount and duration of uterine bleeding were measured at the beginning and end of the study. In addition, the side effects of the pills were evaluated at the end of the study from both groups. Data were analyzed using Chi- square test. Results: Low dose contraceptive pill in vaginal route decreased bleeding amount and duration of bleeding more effectively than oral rout (P<0.05). The side effects of contraceptives, such as nausea and vomiting was significantly higher in orally-used group compared to the vaginally-used group (P<0.05), but vulvo-vaginitis was significantly higher in vaginally-used group (P<0.05). Conclusion: Using the contraceptive pill by vaginal rout is a safe method with few side effects compared with the oral rout.
Keywords: Contraceptive pill, Dysfunctional uterine bleeding, Side effects, Vaginal administration.
Full-Text [PDF 142 kb]   (1348 Downloads)    
Type of Study: Research |
Received: 2011/06/2
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Abbasi F, Mehrabeyan F. Comparative study on the effect of combine low dose contraceptive pills administered by the oral and vaginal routes on bleeding pattern in dysfunctional uterine bleeding. J Shahrekord Univ Med Sci. 2009; 11 (1) :28-34
URL: http://journal.skums.ac.ir/article-1-260-en.html


Volume 11, Issue 1 (spring 2009) Back to browse issues page
مجله دانشگاه علوم پزشکی شهرکرد Journal of Shahrekord University of Medical Sciences
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