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:: Volume 18, Issue 1 (Apr,May 2016) ::
J Shahrekord Univ Med Sci 2016, 18(1): 1-8 Back to browse issues page
Comparison of anti-Mullerian Hormone average between laparoscopic and treatment with clomiphene citrate in patients with polycystic ovarian syndrome
Mohammad Nouri , Esmat Aghadavod * , Laya Farzadi
Kashan university of medical sciences , aghadavod@Kaums.ac.ir
Abstract:   (2822 Views)

Background and aims: Anti-Mullerian Hormone (AMH) has been implicated in the pathogenesis of ovary polycystic syndrome. The aim was to compare AMH average in both laparoscopic and treatment with clomiphen citrate to evaluate an ovulatory response.

Methods: This clinical trial study was administrated on ovulatory women with polycystic ovary syndrome. The patients divided undergoing laparoscopic (n=49), and receiving clomiphene citrate (n=20). Plasma AMH concentrations were measured before and 1 week after treatment and then was evaluated after 3 and 6 month as well. Comparisons of means in each group were performed using ANOVA analysis.

Results: The pretreatment mean of plasma AMH concentrations didn’t have a significant difference between laparoscopic (6.1±4.1) and clomiphene citrate treatment (5.7±3.2) (P>0.05). After laparoscopic treatment, in women who responding to treatment, AMH level was shown a significant reduction (5.6±2.1) compared with the non-responders (9±1.3) (P<0.05). AMH levels didn’t show a significant reduction in the treated patients with clomiphen citrate.

Conclusions: Laparoscopic is successful in patients who AMH levels are lower before treatment.

Keywords: Key words: Anti-Mullerian Hormone, Laparoscopic, Polycystic ovary syndrome, Clomiphene citrate.
Full-Text [PDF 775 kb]   (1234 Downloads)    
Type of Study: Research | Subject: midwifery & Gynecology
Received: 2015/01/3 | Accepted: 2015/09/21 | Published: 2016/04/1
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Nouri M, Aghadavod E, Farzadi L. Comparison of anti-Mullerian Hormone average between laparoscopic and treatment with clomiphene citrate in patients with polycystic ovarian syndrome. J Shahrekord Univ Med Sci. 2016; 18 (1) :1-8
URL: http://journal.skums.ac.ir/article-1-2291-en.html


Volume 18, Issue 1 (Apr,May 2016) Back to browse issues page
مجله دانشگاه علوم پزشکی شهرکرد Journal of Shahrekord University of Medical Sciences
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