در حال انتقال سرور
   [Home ] [Archive]   [ فارسی ]  
:: Main About Current Issue Archive Search Submit Contact ::
:: Volume 16, Issue 3 (Aug, Sep 2014) ::
J Shahrekord Univ Med Sci 2014, 16(3): 70-78 Back to browse issues page
Relation between ghrelin, obestatin and ghrelin to obestatin ratio with bone mineral density in active and non-active men
Akram Jafari *
Islamic Azad University, Shahrekord Branch , jafari.shku@yahoo.com
Abstract:   (7315 Views)
Background and aims: Previous laboratory studies have shown the importance of maintaining sufficient energy status for normal functioning of hormones that regulate bone formation and bone resorption. Ghrelin and obestatin are orexigenic and anorexigenic peptides, respectively that affect energy balance. According to the importance of physical activity in energy balance and bone density, the aim of this study was to investigate the amount of ghrelin, obestatin, ghrelin to obestatin ratio and bone mass density and their relationship in athletes and non-athletes 50 -70 years old men. Methods: In this analytical study, thirty athletes and thirty non- athletes 50-70 years old men took part in this research. Bone mass density of femur and lumbar vertebras were measured by Dual Energy X-ray Absorptiometry (DXA) and ghrelin and obestatin were measured by ELISA method. Results: The result of t-test showed that femur and lumbar bone mass density and ghrelin to obestatin ratio were significant higher in athlete group (P<0.05). The result of Pearson correlation test showed that there was no significant relationship between ghrelin, obestatin and ghrelin to obestatin ratio with bone mass density. Conclusion: Regular participating in exercise training can increase bone mineral density and ghrelin to obestatin ratio in 50- 70 years old men. It seems that the relation between food intake and bone metabolism showed in previous researches is different with the relation between ghrelin, obestatin and ghrelin to obestatin ratio with bone density.
Keywords: Exercise, Ghrelin, Osteoporosis, Obestatin, Regulating energy
Full-Text [PDF 211 kb]   (1397 Downloads)    
Type of Study: Research | Subject: Sport Physiology
Received: 2013/07/28 | Accepted: 2013/09/24 | Published: 2014/06/15
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA code


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Jafari A. Relation between ghrelin, obestatin and ghrelin to obestatin ratio with bone mineral density in active and non-active men. J Shahrekord Univ Med Sci. 2014; 16 (3) :70-78
URL: http://journal.skums.ac.ir/article-1-1628-en.html


Volume 16, Issue 3 (Aug, Sep 2014) Back to browse issues page
مجله دانشگاه علوم پزشکی شهرکرد Journal of Shahrekord University of Medical Sciences
Persian site map - English site map - Created in 0.05 seconds with 31 queries by YEKTAWEB 3792