Sport Physiology Dept., Marvdasht Branch, Islamic Azad University, Marvdasht, I.R. Iran , alihoseini_57@yahoo.com
Abstract: (1590 Views)
Background and aims: Interleukin-17 (IL-17) and interleukin-18 (IL-18) are proinflammatory cytokines. The aim of the present study was to investigate the effect of swimming trainings and detraining on IL-17 and IL-18 of rats. Methods: 60 rats were selected and divided to 5 groups of 12 rats: 8 weeks swimming training, 10 weeks swimming training, 8 weeks control, 10 weeks control and 2 weeks detraining following 8 weeks swimming training. Swimming trainings were included 8 and 10 weeks, 5 sessions per week and 60 minutes per session. For statistical analysis of data used Kolmogorov Simonov, one way ANOVA and Tukey post hoc tests (P≤0.05). Results: 8 (P=0.56) and 10 (P=0.51) weeks swimming training have no significant effect on IL-17 of rats, 8 weeks swimming training has no significant effect on IL-18 of rats (P=0.72). Nevertheless 10 weeks swimming training had significant effect on reduction IL-18 of rats (P=0.005) and 2 weeks detraining following 8 weeks swimming training has significant effect on increase IL-17 (P=0.01) and IL-18 (P=0.001) of rats. Conclusion: Regarding to 10 weeks swimming training reduces and 2 weeks detraining following 8 weeks swimming training increases proinflammatory cytokines, it is concluded training program should not be discontinued to prevent the reveal of inflammation.
Hosseini A, Hassanpour Q, Noura M, Kheirdeh M, araiesh A, Hosseini Z S. The effect of swimming training and detraining on interleukin-17 and interleukin-18 of rats. J Shahrekord Univ Med Sci. 2017; 19 (4) :1-11 URL: http://journal.skums.ac.ir/article-1-3034-en.html