Background and aims: Multiple sclerosis considers as one of the most common neurological diseases. The aim of this study was to evaluate changes in biochemical parameters associated with kidney function, including urea, uric acid and creatinine in patients with multiple sclerosis while taking the drug and compared them with a control group.

Methods: Multiple sclerosis considered as one of the most common neurological diseases. The aim of this study was to evaluate changes in biochemical parameters associated with kidney function, including urea, uric acid and creatinine in patients with multiple sclerosis while taking the drug and compared them with a control group.

Results: The mean serum urea level in case and control was 4.58, 14.38, 4.33 and 13.86 mg/dl, respectively. The mean of acid uric level in patients and control were respectively 0.99, 4.66 mg/dl and 1.06, 4.64 mg/dl. The mean of creatinine concentration in case and control was 0.10, 0.85 and 0.11, 0.78 mg/dl, respectively.

Conclusion: Present study indicated that no statistically significant difference observed in serum levels of urea, uric acid and creatinine, between case and control groups.