Background and aims: Pain is the most popular of mental pressure that human face with. Based on the role of psychological factors in the formation and persistence of chronic pain and disability caused by it, this study was aimed to determine the fitness of cognitive-personality model of generalized anxiety disorder to explain the perception of pain in patients with chronic pain.

Methods: This study was conducted in the context of a correlation research in the type of structural equation. The sample were consisted of 210 patients (146 female and 64 male) referred to a specialized pain clinics in Rasht city that based on clinical interviews had generalized anxiety disorder symptom, and they were selected by available sampling and were completed perception of pain, worry, rumination and neurosis questionnaires. Data were analyzed by using descriptive measures of frequency, percentage, mean, standard deviation and Pearson's correlation coefficient and structural equation model.

Results: The results showed that neuroticism is associated with pain perception by mediated role of worry in people with pain disorder (P<0.01). Also, direct effect of worry and rumination with neuroticism were significant (P<0.01), but the direct effect of rumination with pain perception was not statistically significant (P>0.05).

Conclusion: The research findings revealed that worry and neuroticism variables involved to explaining the perception of pain in patients with chronic pain and generalized anxiety. Therefore, more attention to cognitive and personality structures in the area of chronic pain is necessary.